Genedata Biologics® supports the full protein production process, from definition of the desired protein molecules for production, to molecular biology, expression, purification, and analytics. The system stores all proteins, vectors, plasmids, cell lines, material batches, and related analytics and QC data. It provides tools for molecule and sample registration, as well as analytics and QC data reporting. Vector development campaigns are supported by tools for in silico construct creation for diverse cloning strategies and enable parallel development of both transient and stable cell line pools. All expression and purification samples are related to their underlying experimental protocols.
The integrated and consistent management of expression-relevant data such as promoters, leader peptides, codon usage, and vector design, enable evidence-based optimization and development of expression systems, even for notoriously difficult-to-express proteins. Genedata Biologics can handle diverse antibody formats, including standard IgG, next-gen formats, and other multi-chain proteins and also takes into account modifications such as PEGylations, glycosilations, or conjugations (e.g., for antibody drug conjugates - ADCs).
Analytics and QC data are stored within the same system and are auto-referenced to the relevant expression and purification batches. The system also provides specialized functionalities for the production of tool proteins and antigens. Integrated reporting allows for automatic generation of comprehensive Certificate of Analysis (CoA) reports for release and handover of final protein samples.