Presented at Bio-IT World, May 2014, Boston, MA, USA
Development and Implementation of a Biologics Data Platform
Kai Herrmann, Ph.D., R&D IT Project Manager, BBS-ITS-R&D-HCR-BIO, Bayer Business Services
Biopharmaceuticals are increasingly important in the market for new medicines as they provide many advantages over small molecule-based drugs. The discovery and development of biologics molecules such as monoclonal antibodies and recombinant proteins is a complex and time-consuming exercise, and differs substantially from established small-molecule R&D processes. Hence, totally new IT and data management concepts are required. Here, we report our experience over the last 5 years of developing and implementing an innovative turn-key solution for biologics R&D data management. The goal of the new platform was to increase the number and throughput of large-molecule R&D projects, to establish a shared collaboration platform for data exchange, and to improve the quality of results. We present specific challenges encountered, such as process complexity and diversity, process changes, constant adoption to new discovery technologies, direct instrument and robotics integration, and roll-out and system adoption in a large, globally operating biopharmaceutical organization.