Automated patch clamp and calcium oscillation assays enable high-resolution cell-based measurement of ion channels—essential for important toxicity tests such as cardiac safety, at scale. While advances in high throughput electrophysiology instrumentation have led to a dramatic increase in throughput, they have also resulted in new data analysis bottlenecks when analyzing electrophysiological data.
Supporting the latest electrophysiology instrumentation, Genedata Screener for Ion Channel Screening addresses these bottlenecks, enabling you to:
- Automate sophisticated normalization, averaging and fitting of time-series data, from patch-clamp experiments across millions of compounds, reducing total data handling and analysis time by upwards of 95%.
- Apply any adjustments to calculation windows to downstream results on the fly, for consistent, high-quality analysis.
- View electrophysiology traces from within plate-level visualizations and alongside key results, for rapid QC and assessment.
Customers such as Pfizer and Genentech use Genedata Screener to streamline and automate their high throughput patch clamp screens of up to a million compounds. Learn how AstraZeneca used Genedata Screener to automate and increase the throughput of cardiac safety screens.