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ASMS 2023 — 71th ASMS Conference on Mass Spectrometry and Allied Topics

Houston, TX, USA
June 4–8, 2023
Booth #715

Meet Genedata Experts at ASMS 2023.

Don't miss the opportunity to meet our experts at booth #715 and see how Genedata solutions efficiently support the whole biopharmaceutical R&D workflow, including screening and protein engineering, expression and purification, characterization and analysis of protein therapeutics, cell line design and development, bioprocess optimization, and quality control of biologicals.

Recommended Poster Presentations

Monday, June 5 | 10:30 am – 2:30 pm

MP 176 Head-to-Tail Automation of Covalent Fragment Screening and Hit Characterization by Mass Spectrometry for Rapid Lead Discovery
Jing Xue1; Alexandra Frommlet1; Robert Blake1; Alexis Rohou1; Melinda Mulvihill1; Ke Sherry Li1
1Genentech, South San Francisco, CA

MP 614 Monitoring mAb Proteoforms in Mouse Plasma using an Automated Immunocapture Combined with Top-Down and Middle-Down Mass Spectrometry
Jonathan Dhenin1,2,3; Valérie Lafont2; Mathieu Dupré2; Norbert Zombori2; Alain Krick2; Christine Mauriac2; Julia Chamot-Rooke1,3,4
1Institut Pasteur, Paris, France; 2Sanofi, Chilly-Mazarin, France; 3Université Paris Cité, Paris, France; 4CNRS, Paris, France

MP 628 Top/Middle-Down Protein Sequencing: a Novel Automated Data Processing Tool for the Top-Down/Middle-Down Analysis of Biological Therapeutics
Mona Hamada1, Stefano Gotta2, Wen Jin1, Amy Claydon3, and Amandine Boudreau1
1SCIEX; 2Genedata AG, Basel, Switzerland; 3Genedata Ltd., Cambridge, UK

MP 629 A Single Data Workflow Leveraging Middle-Down Sequencing to Validate Intact Mass Analysis Characterization of Therapeutic Antibodies
Stephen Kok1, Maurizio Bronzetti1, Aude Tartière1, Amy Claydon2, and Arnd Brandenburg3
1Genedata Inc., San Francisco, CA, USA; 2Genedata Ltd., Cambridge, UK; 3Genedata AG, Basel, Switzerland

MP 684 LC-MS Identified Esterification of Glutamic Acid by Sorbitol in a Monoclonal Antibody Stability Assessment
Bin Yu1; Shannon Williams1; Glen Young1
1coherus bioscience, Camarillo, CA

Tuesday, June 6 | 10:30 am – 2:30 pm

TP 039 An Automated MS Data Workflow Enabling Targeted, Site-Specific Glycosylation Monitoring in Continuous Biopharmaceutical Manufacturing
 Diego Bertaccini1
1Merck KGaA, Corsier-sur-Vevey, Switzerland

TP 371 A Streamlined Data Analysis Workflow for Enhanced New Peak Detection (NPD) in the Multi-Attribute Method (MAM)
Maurizio Bronzetti1, Aude Tartiere1, Stephen Kok1, Amy Claydon2, and Arnd Brandenburg3
1Genedata Inc., San Francisco, CA, USA; 2Genedata Ltd., Cambridge, UK; 3Genedata AG, Basel, Switzerland

TP 575 Automated Data Analysis Workflow Leveraging PASEF Data Accelerates Confident Detection of Low-Abundance HCPs
Amy Claydon1, Guillaume Tremintin2, Juergen Kastler3, Stuart Pengelley4, Jonathan Krieger2, and Arnd Brandenburg3
1Genedata Ltd., Cambridge, UK; 2Bruker Daltonics, San Jose, USA; 3Genedata AG, Basel, Switzerland; 4Bruker Daltonics, Bremen, Germany

Wednesday, June 7 | 10:30 am – 2:30 pm

WP 044 Implementation of Multi-Attribute Method in the Context of Continuous Biopharmaceutical Manufacturing: from Clone Selection to Analytical Support in GxP Runs
Mélanie Jakobczyk1
1Merck KGaA, Darmstadt, Germany, Corsier-Sur-Vevey, Switzerland

Thursday, June 8 | 10:30 am – 2:30 pm

ThP 233 Automated Data Analysis and Robust Quality Control for Affinity Selection Mass Spectrometry
Matthew Green1, Juan Florez2, Malwina Michalak, Stephan Steigele2 , Stephan Heyse2
1Genedata Ltd., Cambridge, UK; 2Genedata, Basel, Switzerland; 3Genedata, Munich, Germany

ThP 580 A Fully Automated, Sample-Specific Data Workflow for High-Throughput Identity Testing of Oligonucleotide Therapeutics
Aude Tartiere1, Maurizio Bronzetti1, Stephen Kok1, Amy Claydon2, and Arnd Brandenburg3
1Genedata Inc., San Francisco, CA, USA; 2Genedata Ltd., Cambridge, UK; 3Genedata AG, Basel, Switzerland

To schedule a meeting in advance or receive more information on Genedata Expressionist, please contact expressionist(at)genedata.com.