In-Depth Proprietary Genome Annotation
A well-annotated genome as a reference is the basis for accurate multi-omics analysis, genome editing, TLA analysis, and even biosafety testing.
The Genedata Selector® team can support you with comprehensive annotation of your proprietary genomes for:
- Public domain data integration of cell line-specific genomes, transcriptomes, and proteomes
- Molecular and signaling pathways
- Splice variants and microRNAs
- Mutations and CNVs
Characterizing Cell lines with Single Cell RNA Sequencing
Single-cell RNA Sequencing (scRNA-seq) is highly useful in the production of biotherapeutics that rely on cell lines such as recombinant proteins and cell therapies. Genedata Selector enables you to leverage advanced algorithms for simplified and automated analysis of scRNA-seq data and individual cell line transcriptome quantification. With the sophisticated visualizations and automated comprehensive reports in Genedata Selector, you can assess cell line heterogeneity and ensure cells maintain the desired attributes to generate high-quality products.
TLA-Based Integration Site Detection
Confirm gene editing events, track transgene integration sites, and select stable clones for production using TLA. Data processing capabilities of Genedata Selector allow clone selection based on the location of the integration site and the assessment of integration site genetic stability.
CRISPR-Based Targeted Engineering
Predict tested and quality-controlled guide RNAs for genetic engineering of your proprietary genomes. Genedata Selector ensures a secure environment with reduced IP risk and provides valuable information such as gRNA specificity scores and a list of high-quality primer sequences ready-to-order.