Genedata Selector® streamlines the analysis and interpretation of NGS data for cell line development applications. Key applications include the confirmation of clone identity, refinement of host cell lines, and the verification of product integrity, stability, and purity.
In-Depth Proprietary Genome Annotation
A well-annotated genome as a reference is the basis for accurate multi-omics analysis, genome editing, TLA analysis, and even biosafety testing.
The Genedata Selector® team can support you with comprehensive annotation of your proprietary genomes for:
- Public domain data integration of cell line-specific genomes, transcriptomes, and proteomes
- Molecular and signaling pathways
- Splice variants and microRNAs
- Mutations and CNVs
Characterizing Cell Lines with scRNA-seq
Assess cell line heterogeneity and ensure cells maintain the desired attributes to generate high-quality products using Single-cell RNA Sequencing (scRNA-seq). With the sophisticated visualizations and automated comprehensive reports in Genedata Selector, you can simplify and automate the analysis of individual cells.
Learn in 3 minutes how to characterize your cell line with Single-cell RNA Sequencing:
TLA-Based Integration Site Detection
Confirm gene editing events, track transgene integration sites, and select stable clones for production using TLA. Data processing capabilities of Genedata Selector allow clone selection based on the location of the integration site and the assessment of integration site genetic stability.
Learn in 3 minutes how to simplify the analysis of Cergentis TLA technology:
CRISPR-Based Targeted Engineering
Predict tested and quality-controlled guide RNAs for genetic engineering of your proprietary genomes. Genedata Selector ensures a secure environment with reduced IP risk and provides valuable information such as gRNA specificity scores and a list of high-quality primer sequences ready-to-order.
Learn in 6 minutes how to optimize CRISPR guide RNA predictions: