Enabling the systematic design, cloning, and testing of large numbers of bi- and multi-specifics, such as knobs-into-holes (KinH), Fab-scFv, IgG-scFv, DuoBody, DVD-Ig, tandem-scFv-Fc and their parametric variants (e.g., linkers, V-domain order, Fc).
Bispecific Antibody Engineering
Genedata Biologics automates downstream expression, purification, and characterization processes, which substantially increases throughput. By identifying the most successful combination of antigen binders and formats, the platform resolves major bottlenecks in high-throughput molecular biology and cloning processes and directly integrates with laboratory automation equipment to scale up cloning and production. With the automatic aggregation of all assay and analytics results, the platform also enables multi-parameter lead selection.
Genedata Biologics gives all our R&D groups a central place to record and access TCR-related information in real time, along the end-to-end workflow.
Dominik Maurer, Ph.D. VP Immunology
Given their track-record of success, Genedata’s platform was the clear choice to support and integrate our full cell therapy discovery and development efforts.
“We are rapidly expanding our biotherapeutic R&D activities and needed a scalable, flexible platform that we could quickly and easily implement. We chose Genedata Biologics as it is the only out-of-the-box platform on the market dedicated to large-molecule R&D.”
"We made a decision early on to use Genedata Biologics as MorphoSys’ workflow backbone to accelerate our drug discovery efforts and have watched as Genedata Biologics has become the global industry standard for biopharma discovery organizations."