Mass Spectrometry Analysis. Streamlined.
Why has mass spectrometry (MS) become an essential analytical technology throughout biopharma? MS is highly sensitive, widely applicable, and delivers information-rich data that provides insights at the molecular level. However, MS instruments generate large and complex data sets that can accumulate very quickly and require robust bioinformatic approaches for processing, analysis, and reporting.
This is where Genedata comes in.
Our Customers
- Any Instrument. One Platform.
- Automation. Harness its Power.
- Efficient Analysis. MAM.
- Out-of-the-Box. Flexible & Tailored.
- Product Quality. Regulatory Standards.
Any Instrument. One Platform.
- Streamline and automate MS analysis from any instrument on a single platform to deliver high-quality and reproducible results and harmonize MS analysis across the organization.
- Leverage a best-in-class analysis and reporting solution with intuitive visualization for accurate interpretation of results and faster decision-making.
- Reduce development costs, improve attrition rates, and speed up time to market by accelerating processing of MS data sets of all sizes in a resource- and time-effective manner.
- Easily identify data of interest and analyze and visualize directly using point-and-click analytical solutions or purpose-built dashboards.
- Use cutting-edge algorithms and unique out-of-the-box visualizations to perform in-depth structural analysis of entire proteins or high-throughput screening for comprehensive characterization of complex modalities.
Automation. Harness its Power.
- Automate repetitive and laborious procedures and overcome data processing bottlenecks while maintaining complete control of every processing step.
- Automatically review results and facilitate interpretation and understanding with intuitive visualizations that link raw and processed data.
- Automate MS data intake and processing and combine diverse omics data (e.g., proteomics, metabolomics, lipidomics) for integrative analyses.
- Leverage robotic users to find and process MS data in real time and exchange information with different data systems to support unattended 24/7 operations.
- Bridge instruments, laboratories, and global teams by seamlessly integrating with existing data infrastructure and processes in one system.
Efficient Analysis. MAM.
- Deliver significant time savings, improve consistency, and simplify data review by automating MS data analysis and reporting.
- Leverage scientific expertise to design and implement ready-to-use and fully automated Multi-Attribute Method (MAM) workflows.
- Support the entire MAM process — from upstream in-depth characterization to downstream targeted critical quality attribute monitoring — on a single integrated software platform.
- Empower routine MAM users with limited MS experience to independently perform data analysis based on clear and well-defined processes.
- Multiply expertise within the team by reusing workflows across multiple scenarios and projects to extend the reach and impact and to democratize access to MS.
Out-of-the-Box. Flexible & Tailored.
- Leverage ready-to-use building blocks to create custom workflows that are lockable and fully traceable through an audit trail. Use AI to eliminate manual steps in MS data processing.
- Perform mass analysis of intact antibodies and their subunits using advanced and proprietary algorithms to remove artifacts or differentiate coeluting species.
- Analyze peptide mapping out-of-the-box by automatically combining relevant sequence information with MS results and efficiently quantify post-translational modifications, sequence variants, and glycosylation.
- Perform comprehensive, accurate, and fast glycoanalysis using reference and custom glycan libraries resulting in detailed structural information including glycan composition, glycosylation sites, sequence, and branching.
- Detect host cell proteins (HCPs) and uncover unexpected contaminants and product variants through new-peak detection. Identify liabilities earlier.
Product Quality. Regulatory Standards.
- Get end-to-end support to operate in a GxP environment with validation-ready compliance capabilities.
- Streamline computer system validation testing by using templates for qualification tests.
- Automatically perform process-specific system suitability tests (SSTs) and monitor deviations in instrument performance for seamless product quality assessments with minimal process downtime.
- Obtain all necessary compliance functionalities out-of-the-box, including secure client-server communication and full audit trail.
- Automate results review and custom report generation to meet specific needs and comply with complex regulatory reporting standards and requirements.
Customer Stories
Automated Workflows for Peptide Mapping Analysis
Learn how Johnson & Johnson scientists use automated workflows and metadata to enhance peptide mapping, reduce variability, and standardize reporting for better data aggregation and confidence
High-Throughput Assay for Multispecific Antibodies
Discover how Sanofi uses automated high-throughput intact mass spectrometry wokflows to detect and quantify mispaired species in multispecific antibodies, enabling analysis in just three weeks.
Automated High-Throughput Covalent Binding Analysis
Learn how AstraZeneca and Genedata automate covalent drug discovery and high-throughput screening, maximizing MS analysis benefits, boosting throughput, and cutting costs.
Automating Biotherapeutic Characterization
Discover how automated MS data workflows enhance productivity, harmonize analysis, eliminate errors, and facilitate collaboration in biopharmaceutical developability assessments at Novartis.