Cell Therapies
Do you want to develop CAR-Ts, TILs, TCR-Ts and iNKs faster and more cost efficiently? Do you need to streamline design, generation, and testing of these complicated modalities? Do you need to trace, protect, and analyze vast amounts of complex and often personalized data?
This is where Genedata comes in.
Our Customers
- Cell Therapy Discovery. Automated.
- Cell Engineering. Precise.
- Bioprocess Development. Simplified.
- Biosafety. Maximum Efficacy.
- Translational Research. Enhanced.
Cell Therapy Discovery. Automated.
- Capture structured data along the entire discovery workflow in accordance with FAIR data principles.
- Integrate all information including the specificity, efficacy, safety, stability, manufacturability, and scalability parameters, to facilitate efficient selection of lead molecules and cell lines.
- Screen, engineer, produce, test, and validate each candidate in a central location shared across groups.
- Automate sample handling and testing procedures by directly and easily integrating with laboratory equipment.
Cell Engineering. Precise.
- Design and optimize any molecule format such as CARs and TCRs in the molecule workspace.
- Modify cells according to therapeutic purpose and automatically generate novel expression vectors and gene delivery systems in silico.
- Streamline and automate workflows and confirm integration sites to select the best cell lines for production.
- Quickly identify top candidates based on multiple selection criteria to find the most promising clones to pursue in development.
Bioprocess Development. Simplified.
- Track bioprocess development for all cell therapy components including recombinant proteins, adoptive cells, and viruses.
- Establish next generation biomanufacturing processes and accelerate analytics development for autologous as well as allogeneic cell lines.
- Track and rigorously characterize the relationship between critical quality attributes and critical process parameters.
- Centralize analytics development from all instruments and assays to transparently assess the effects of process parameters on product quality.
- Integrate all laboratory devices including bioreactors, chromatography skids, and liquid handling systems for efficient data transfer and automation.
Biosafety. Maximum Efficacy.
- Make routine biosafety testing reproducible and faster using automated NGS-based workflows to easily assess correct insertion of genes, cell type potency, heterogeneity and to detect adventitious agents.
- Validate all automated NGS workflows in a GxP environment with the help of validation support services.
- Use pre-configured custom go/no-go rules to automatically flag samples that do not meet the required stability, purity, and potency standards.
Translational Research. Enhanced.
- Facilitate novel insights by enabling seamless integration, advanced performant analytics, and sophisticated visualization of clinical and translational data.
- Characterize patient and donor profiles at molecular, immune, and clinical levels to develop more efficacious and safer cell therapies.
- Discover and validate new biomarkers of toxicity, efficacy, or risk of relapse.
- Track patient-specific data before and after the administration of cell therapies to anticipate and prevent adverse effects, ensure safety, and maximum therapeutic benefit.
- Leverage RWE to monitor health and long-term treatment benefits.
Customer Stories
Immatics Boosts CGT R&D Efficiency
“Genedata Biologics provides our R&D teams with a centralized platform to record and access TCR data in real time, enhancing efficiency across the entire workflow.” Dominik Maurer, Ph.D., VP of Immunology, Immatics.
Advancing Cell Therapy with NGS Implementation
Characterizing cell therapy products and ensuring biosafety is crucial. Find out how Astellas and Genedata collaborated to enhance data integration and decision-making.