Antibody Drug Conjugates

Do you need help designing and optimizing ADC components, including the antibody, payload, linker, and conjugation chemistry, to achieve the right balance between clinical efficacy and tolerability? Do you want to automate and track each step of construction and analyze all assay results throughout the ADC workflow in a single integrated system?

This is where Genedata comes in.

Request a Demo

Discovery. Accelerated.

Screen small molecules, optimize antibodies, and test ADC activity more efficiently thanks to automated raw data processing, streamlined data management, and integrated hit-selection tools.
Accelerate library-based screening and clone selection with automated library management, deconvolution tools, and automated plate handling.
Efficiently assess candidate molecular interactions and stability with built-in molecular characterization and biophysical screening tools.
Track all antibody formats, conjugates, and modification steps with advanced workflow-based large molecule registration system.

Engineering. Simplified.

Design molecular templates in any format without copy-pasting sequences and simplify the design and construction of all candidate ADCs.
Automate the design of new DNA constructs and DNA synthesis workflows and track their production and site-specific linker conjugation.
Automatically verify the synthesized sequence material against the original molecule design.

Production. Scaled Up.

Track all batches throughout purification and conjugation and gain a transparent and accessible view for all teams.
Integrate all instrument characterization data enabling automated quality control and comprehensive candidate evaluation.
Support go/no-go decision-making with real-time display of results within interactive dashboards.

Biosafety. Ensured.

Improve contaminant detection in biosafety testing to better confirm purity, efficacy, and stability.
Use built-in data quality control to simplify the generation of clear, actionable insights that support decision-making.
Integrate into GxP environments with built-in documentation, controlled user records, and timestamped transaction records to ease the regulatory submission process.

Clinical Benefit. Maximized.

Identify new predictive biomarkers by integrating molecular assay data from ADC development with treatment response and clinical data in a dedicated multiomics platform.
Find patients less likely to respond due to alterations in drug metabolism, target proteins, or signaling pathways using advanced analysis tools.

The platform can register and organize all samples that are relevant according to the ADC of interest, such as vectors and expression constructs, developed cell lines, expression and purification batches, linkers, and cytotoxins.

1 / 1