Optimizing ADCs
Advance your antibody-drug conjugate development.
Automate and track each step of the design and optimization of ADC components and analyze all assay results in a single integrated system for balancing clinical efficacy and tolerability. With Genedata.
Our Customers
- Discovery. Accelerated.
- Engineering. Simplified.
- Production. Scaled Up.
- Biosafety. Ensured.
- Clinical Benefit. Maximized.
Discovery. Accelerated.
- Screen small molecules, optimize antibodies, and test ADC activity more efficiently thanks to automated raw data processing, streamlined data management, and integrated hit-selection tools.
- Accelerate library-based screening and clone selection with automated library management, deconvolution tools, and automated plate handling.
- Efficiently assess candidate molecular interactions and stability with built-in molecular characterization and biophysical screening tools.
- Track all antibody formats, conjugates, and modification steps with advanced workflow-based large molecule registration system.
Engineering. Simplified.
- Design molecular templates in any format without copy-pasting sequences and simplify the design and construction of all candidate ADCs.
- Automate the design of new DNA constructs and DNA synthesis workflows and track their production and site-specific linker conjugation.
- Automatically verify the synthesized sequence material against the original molecule design.
Production. Scaled Up.
- Track all batches throughout purification and conjugation and gain a transparent and accessible view for all teams.
- Integrate all instrument characterization data enabling automated quality control and comprehensive candidate evaluation.
- Support go/no-go decision-making with real-time display of results within interactive dashboards.
Biosafety. Ensured.
- Improve contaminant detection in biosafety testing to better confirm purity, efficacy, and stability.
- Use built-in data quality control to simplify the generation of clear, actionable insights that support decision-making.
- Integrate into GxP environments with built-in documentation, controlled user records, and timestamped transaction records to ease the regulatory submission process.
Clinical Benefit. Maximized.
- Identify new predictive biomarkers by integrating molecular assay data from ADC development with treatment response and clinical data in a dedicated multiomics platform.
- Find patients less likely to respond due to alterations in drug metabolism, target proteins, or signaling pathways using advanced analysis tools.
Selected Case Studies
Digitalization & Automation Across mAbs, Bispecifics & ADCs
Merck has revolutionized biotherapeutic discovery by automating R&D workflows, integrating Genedata Biologics to streamline data management and accelerate mAbs, Bispecifics, and ADCs development.
ADC Therapeutics Accelerates R&D with Genedata
“We were thrilled to find a commercial digital platform purpose-built for ADC workflows that supports our proprietary conjugation and linker technologies out-of-the-box.” Patrick van Berkel, Ph.D.
Daiichi Sankyo Automates Novel Biological Therapeutics Discovery
Daiichi Sankyo adopted Genedata Biologics to automate and accelerate biologics discovery, integrating complex research processes and enabling data-driven decisions.