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Robust and Versatile New Peak Detection Workflow to Facilitate MAM Implementation

June 2, 2025

New Peak Detection (NPD) is essential for MS‑based Multi‑Attribute Method (MAM) workflows, yet false positives and high review effort often limit its use in GMP environments. This poster presents a sensitivity‑optimized NPD workflow implemented in Genedata Expressionist®, combining enhanced statistical scoring, Known Peak Lists, replicate analysis, and rule‑based artifact flagging to dramatically reduce false positives.

You will learn how improved robustness, usability, and automation enable reliable identification of true sample changes, support non‑expert users, and facilitate MAM adoption from research through commercialization.

Learn more about the topic:

Enabling MS-based MAM in QC Through a Robust New Peak Detection Workflow

Development, qualification, and application of a highly efficient and robust new peak detection workflow for the LC-MS peptide mapping multi-attribute method


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