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A Single Data Processing Platform that Enables Novel MS-based Methods for In-depth Characterization of Biopharmaceuticals

This case study focuses on the work of the Merck Serono structural characterization laboratory in Guidonia, Italy, and describes how they developed novel and efficient MS-based methods for the analysis of charge-variants, glycoforms, and released glycans in biopharmaceuticals. Optimizing sample prep and separation procedures and streamlining MS data processing, analysis, and management enabled in-depth characterization with time-savings of up to 80% compared to conventional methods.

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