Developing a generic, high-throughput assay for characterization of DuoBody® Bispecific Ab samples using Genedata Expressionist®

Using Genedata Expressionist, scientists at Genmab established an automated MS-based high-throughput assay that provides qualitative and quantitative information on a bsAb preparation in a fraction of the time and effort required by conventional CEX-based methods. Compared to the CEX-based process, the time required for data acquisition and processing was reduced by 95% and the number of person hours dedicated to data processing was reduced by 70%.

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