Intact and Subunit Mass Analysis
Intact mass analysis enables identification and quantification of entire antibodies and their subunits, and comprehensive characterization of charge variants, antibody-drug conjugates, and protein glycoforms. The refined MaxEnt charge deconvolution algorithm built into Genedata Expressionist dramatically reduces the number of harmonic artefacts.
A unique time-resolved deconvolution algorithm offers unparalleled analysis of coeluting species, literally adding another dimension to insights available to Genedata Expressionist users.
Request the Genmab Case Study
Glycosylation is a critical quality attribute that affects biotherapeutic efficacy and safety. Genedata Expressionist enables rapid and efficient identification of released glycans and characterization of glycosylated peptides and proteins using reference or custom glycan libraries.
An intuitive built-in editor facilitates the addition of complex glycan moieties that are typically absent from generic databases. Using Genedata Expressionist for MS-based glycoanalysis has been shown to deliver time-savings of up to 80% compared to conventional methods.
Request the Merck Case Study