Genedata Biologics

Extension Modules

Additional modules offer extended support for biopharmaceutical discovery workflows.

The Request Management Module, tailored specifically to the needs of large molecule R&D workflows, increases operational efficiency by streamlining requesting and task managing processes. It tracks the full lifecycle of task scheduling and enables a central and real-time overview of the progression of all requests. The module is used to prioritize, schedule, and fulfill complex, iterative, multi-step requests and to communicate status updates for each task to ensure that all steps are completed on time. By standardizing and simplifying intergroup communication, it facilitates seamless collaboration in a division-of-labor environment in which completion of experiments requires the close interaction of many specialized groups, such as molecular biology, expression, purification, analytics, and assay teams, plus the integration of tasks performed by CROs and other external collaborators.

Specialized request planning and tracking dashboards for each group provide comprehensive overviews of all requests and their status and facilitate the prioritization and planning of activities. The module provides direct and detailed background information about the request (e.g., records of the requested proteins, expression constructs, cell lines) as well as drill downs to related information, such as data from previous experiments performed by other groups (e.g., expression system used and titers). Automated email notifications provide timely updates to all involved parties and trigger specific actions along the overall progression of a request through the organization, based on configurable and pre-defined cascades depending on e.g., the protein format (mono/bispecific therapeutics, reagents) or cell line type.

The Patent Module facilitates and streamlines the generation and submission of patent applications. Submissions for large-molecule patents typically contain large numbers of sequences and various combinations of sequence segments. The process of compiling and annotating these sequence lists can be time consuming at best, and in the worst case, errors may go unnoticed until after the patent application has been published. In fact, a substantial number of published patent applications contain serious errors with a significant business impact. Typical errors include cases in which the CDR or variable domain combinations are not unique and unintentionally claimed redundantly within a patent application or a CDR or variable domain definition are not consistent between the patent application text and the sequence listing. Other typical errors are having individual sequences concatenated instead of listed as separate sequences or listing incorrect sequence variants. The Patent Module helps to prevent such errors by automatically tracking, annotating, processing, and properly formatting all relevant sequences for patent applications. The system increases quality and eliminates costly mistakes in patent applications by systematically tracking, organizing, annotating, and reporting all relevant sequences. It provides the necessary flexibility to extend sequence listings during the patent extension period until the final sequence listing submission, and once submitted, lock all the data to the document to 'freeze' the final submission. Finally, the platform facilitates the final submission as it automates the generation of sequence list reports ready for patent submission via direct integration with standard submission tools such as the PatentIn software.

The Patent Module is equally useful for scientists, inventors, and patent counsels and lawyers who jointly work on patent submissions and provides a clear and accurate common vocabulary for referencing molecules that are relevant for each patent submission.