Genedata Biologics

Making Biopharma Discovery Faster & Better

Enterprise system for biologics R&D

Genedata Biologics™ is a first-in-class workflow system that boosts the efficiency of the biologics discovery process. Uniquely designed from the start for large molecules, the system increases throughput and quality during the biologics discovery process and covers therapeutic antibodies, bispecifics and other next-generation molecules, antibody drug conjugates, and therapeutic proteins. The platform supports the full breadth of the large-molecule research process - from screening, protein engineering and optimization, expression, purification, analytics and QC, to candidate developability and manufacturability assessment.

Genedata Biologics supports the design and engineering of superior therapeutic molecules and identifies the best molecules to move forward. By tightly integrating the process of candidate screening, engineering, testing, and selection, the system enables a simultaneous optimization of biological parameters as well as developability and manufacturability parameters, which reduce the risk of encountering unexpected obstacles during development.

Users report up to 50% gains in efficiency and throughput as well as improved quality of results. This is accomplished by tracking and managing all molecule, sample, and testing data in one shared system. A built-in large-molecule registration engine provides unique identification and naming of all biological entities, including proteins, cell lines, and plasmids. All data is shared, making the handover of samples and molecules between collaborating teams more efficient.

The platform simplifies and streamlines the underlying laboratory logistics processes, such as cloning, sequence and sample management, and instrument operation. It directly interfaces with laboratory instruments, facilitating data exchange and streamlining laboratory instrument operation. Full barcoding and automation support enable true high-throughput candidate screening, protein expression, purification, and characterization.

Designed as a scalable enterprise solution, Genedata Biologics simultaneously supports hundreds of users, working in a multi-site, cross-department, and division-of-labor environment. The system works out-of-the-box in its default configuration, can be easily integrated with corporate-specific instrument and IT environments, and is available for both single groups as well as large, global installations.


 

Benefits

Supports all critical steps in the biologics R&D process – including library management, selection and screening, engineering and optimization, cloning, expression and purification, and analytics and QC

Enables efficient design and testing of novel therapeutic candidates – including IgGs, Fabs, scFv, bi- and multi-specifics, next-gen Ab formats, Ab fusion proteins, Fc-engineered molecules, new scaffolds, antibody drug conjugates (ADCs), and non-antibody therapeutic proteins

Technology and process independent – supports phage and yeast display, hybridoma, B-cell cloning, and other discovery technologies and workflows in a single platform

Enables large-molecule registration – for any biologics entity, including antibodies, therapeutic proteins, antigens and other tool proteins, plasmids and DNA, cell lines

Provides integrated management of protein and nucleotide sequences, including CDR / FW auto-annotations, prediction of chemical liabilities, PTMs, or calculation of physical-chemical properties

Facilitates high-throughput workflows via fully barcoded and automated workflows in a system with proven processing and querying speed

Provides sample management - including full-fledged inventory management for aliquot handling, as well as integration with request management systems

Manages and analyzes all assay and analytics data in one system, enabling direct access to all laboratory analysis results for any given sample

Interfaces directly with laboratory instruments, simplifying instrument control and data exchange

Enterprise system that scales with hundreds of users and highest data volumes; includes interfaces to support external workflows with CROs and CMOs