All Assays.
One Digital Platform.
Genedata Screener® automates assay analysis, validates raw data and assay result quality, and consolidates assay information across the enterprise and external collaborators. By integrating and condensing complex experimental data, it powers project decisions and lays the foundation for more predictive, AI-driven, drug discovery and development.
Our Customers
Genedata Screener is a great piece of software that makes MS data processing and analysis super-fast. Its visualizations are fantastic, enabling me to explore everything from detailed mass spectra all the way to plate level analyses
Genedata Screener is flexible and scalable, satisfying all our needs for high, medium, and low experimental throughputs
We believe that Genedata Screener is the gold standard for screening data analysis.
Genedata Screener is one of the standard screening platforms for many of our pharmaceutical customers.
Genedata Screener helps us to access unexplored biology that can’t be examined any other way.
Selected Applications
- High-Throughput Screening
- Large Molecule Assays
- High Content Assays
- Multiplexed Assays
- Biophysical Characterization & Screening
- Pharmacological & Mechanistic Analysis
High-Throughput Screening
Streamline your research from primary screening to hit validation and lead development with Genedata, enabling you to scale using biochemical, biophysical, and cellular assays, as well as other cutting-edge screening modalities. This includes exciting new label-free technologies such as high throughput mass spectrometry.
Explore how end-to-end automation and data-driven decisions are revolutionizing the future of screening, making it faster and easier than ever before.
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Large Molecule Assays
Advance your research with large molecules, one of the fastest growing and most exciting modalities in drug discovery, promising more targeted and highly personalized therapy. Large molecule discovery and development involves multiple stages of engineering and molecule optimization, all of which require a range of targeted and functional assays for molecule assessment.
In addition to many standard assays used across pharma discovery, the Genedata platform supports several assays key to the large molecule discovery workflow, such as plate-based immunoassays and cellular assays, high throughput flow cytometry, epitope binning, and biophysical assays including SPR and BLI.
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High Content Assays
Revolutionize drug discovery with image-based high content screening (HCS). By combining a target-agnostic approach, more physiological models, and information-rich images, HCS can uncover new therapeutic avenues—but brings the challenge of understanding high volume, multiparametric data.
Genedata offers an end-to-end solution for high content screening analysis, making it fast and easy to interpret HCS data or apply HCS across the pipeline.
Multiplexed Assays
Harness the power of image-based high content screening. High content, data-rich assays yield tens or even hundreds of measurements per sample, providing more information to uncover new leads missed by single-endpoint approaches and achieve a more complete characterization of lead molecules.
However, this wealth of information poses challenges for data processing, requiring a solution that facilitates both QC and interpretation of multidimensional results. Genedata supports such multiplexed assays, including flow cytometry, transcriptomic, and combination screening, ensuring efficient and reliable data analysis.
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Biophysical Characterization & Screening
Enhance your research capabilities with optimized image-based high content screening. Biophysical screens utilize a wide range of technologies, including impedance, SPR, BLI, TSA, and more, to characterize molecular interactions and stability, or increasingly, to screen based on such properties. These technologies are served by diverse instruments offering disparate analysis methods, often requiring manual step-by-step processing or lacking batch-analysis for multiple plates. Typically, users must export data to downstream analysis programs, only to return to instrument software to adjust parameters, re-export, and re-run the complete tool sequence.
Genedata streamlines the characterization and screening process by offering ready-to-go workflows.
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Pharmacological & Mechanistic Analysis
Reduce risks in drug discovery with advanced image-based high content screening. Poor toxicity profiles and PK/PD can quickly derail a once-promising lead, turning it into a dead end. Prevent this with rigorous ADME-Tox, kinetic characterization, and target engagement studies early in the discovery pipeline to greatly increase your chances of success.
The Genedata platform helps you achieve this by standardizing and automating the analysis of your in vitro ADME, toxicity assays, and mechanism-of-action studies, ensuring reliable and efficient results.
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Automation
Embrace the Lab of the Future concept to innovate drug discovery and development. By leveraging advanced digital tools and contextualizing your scientific data, you can make research processes more efficient and future-proof. Digitalize and automate your data workflows: automatically retrieve all assay data and metadata from instruments, analyze and quality-control them, and report results to your global team.
With data that is FAIR (Findable, Accessible, Interoperable, Reusable) and AI-ready, Genedata is optimally positioned to provide a digital backbone for your modern lab of the future and help you do science more efficiently.
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Assay Data Management & Decision-Making
Lay the right foundations today to create the therapies of tomorrow, starting with good data management. Many R&D decisions rely on assay data, which is often scattered across the enterprise and external collaborators. Structuring, annotating, and consolidating assay information and results is crucial.
Genedata excels at this, paving the way for data-driven decision-making, AI-powered predictions, and beyond.
Learn MoreUnify Analysis into One Platform.
In Genedata Screener, bring together results for any therapeutic modality—including for biotherapeutics and small molecules—or disease area into one place. Screener covers an unparalleled number of assay technologies with scientifically validated solutions and lets you centrally specify workflows ahead of time, helping harmonize your analysis. Automated reporting and data management with Screener ensures result availability and findability.
- Streamline workflows using one analysis platform for all instruments and technologies.
- Collaborate internally or with CROs and external partners using data securely shared on internal servers, hosted servers, or in the cloud.
- Optimize decision-making by standardizing reporting to data warehouses and annotating results with controlled vocabulary to enable future querying and interpretability.
Shorten R&D Cycles. Do More.
Genedata Screener helps you scale up assays and their analysis so that you can accelerate discovery. In just minutes, this powerful software handles huge or complex datasets by automating data capture, routine calculations, and multi-level quality control.
- Instantly initiate analysis upon experiment completion, using raw data imported directly from the instrument via one of our many standard integrations and plate information via our intuitive import wizards.
- Optimize assays for production-scale execution, with rapid on-the-fly adjustment of processing steps and functionality for comparison of different assay conditions and runs.
- Get straight to final per-molecule results with automated analysis and home in on promising leads from the get-go, using sophisticated assays enabled by Genedata curve-fitting, model selection, and multiplexing capabilities—at scale and early in the discovery cycle.
Ensure Data Quality.
Advance Your Science.
High-quality, reliable results are integral to successful research. Genedata Screener enforces standard QC criteria, pinpoints experimental problems, flags suspect data, and lets you inspect results and optimize analysis parameters as required—automatically recalculating any affected results across the entire dataset. Screener also incorporates knowledge from the forefront of science, putting the most current analysis methods at your fingertips.
- Reduce manual errors and interpretation mistakes.
- Enforce best-practice, scientifically-sound analysis rules using built-in business logic and advanced fitting algorithms and data models.
- Interactively and flexibly perform additional QC using clear, intuitive, dynamic visualizations.
