Genedata Screener for HCS Advances Phenotypic Screening

Single-platform solution fulfills promise of phenotypic screening with full access to and integration with images, raw data, and data warehouses from different vendors

San Francisco, Calif., January 8, 2013

Genedata, a leading provider of advanced software solutions for drug discovery and life science research, today announced it will demonstrate Genedata Screener’s phenotypic screening capabilities at the 10th Annual High Content Analysis (HCA) Conference.  Genedata Screener for High Content Screening (HCS) covers complete screening analysis from cell-level data to final campaign results. Integrating with leading HCS instruments, Genedata Screener simultaneously supports multiple HCS image acquisition and analysis systems while eliminating data analysis bottlenecks and providing instant image access throughout the data analysis pipeline. Genedata Screener for HCS will be demonstrated at the 2013 HCA Conference (Fairmont Hotel; Booth #32) and will be featured in the HCA Technology Showcase on January 9.

Fulfilling the Promise of Phenotypic Screening
While HCS has become routine in drug discovery, the integration of HCS data and images into the data analysis workflow presents challenges. For example, maintaining different instruments and HCS data management systems and deploying separate image analysis solutions consumes time and resources. Additionally, this model often relies on manual workflows with inadequate image access and limitations in throughput or complexity, all of which results in lower productivity and potentially sub-optimal data analysis results. When HCS images are stored in isolated, instrument-specific image data management systems, there is little or no integration with a central-results data warehouse; relevant results are stored without a reference to the original image data.

Genedata Screener for HCS overcomes these workflow challenges. Simultaneously integrating with multiple HCS systems (e.g. PerkinElmer Columbus™ Image Data Management, Thermo Scientific Cellomics® Store database, Molecular Devices MDC Store™ Data Management, openBIS for HCS), Genedata Screener for HCS:

  • captures and stores all HCS data analysis images and image analysis results;
  • enables interactive definition and analysis of cell populations and the automatic calculation of  cell-to-well aggregations;
  • unifies HCS data analysis workflow including efficient quality control;
  • gives instant access to HCS images all along the data analysis workflow; and
  • provides a stand-alone image viewer for downstream applications access to images, even across different geographies.

“With more than a decade of customer experience, best practices, and industry collaboration, Genedata Screener is the most innovative and powerful HCS solution on the market,” said Dr. Othmar Pfannes, CEO of Genedata, “and the solution’s ability to support phenotypic screening demonstrates how it is continually evolving to meet customer demands while advancing the discovery of novel therapies.”

Editorial Note: HCA Technology Showcase – “Get the Big Picture in Phenotypic Screening for Drug Discovery” – January 9, 2013; 2:15pm – 2:45pm. Demonstration of data management workflow from initial capture to result-mining of past experiments.