PEGS Boston - Protein and Antibody Engineering Summit

May 1 - 5, 2017
Boston, MA

Meet Genedata experts at PEGS Boston Protein Engineering Summit in Boston, MA.

Don't miss the opportunity to see how Genedata solutions efficiently support the whole biopharmaceutical R&D workflow, including screening and protein engineering, expression and purification, characterization and analysis of protein therapeutics, cell line design and development, bioprocess optimization, and quality control of biologicals.

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Recommended Oral Presentation

Design and Evaluation of Next-Generation Biologics for Cancer Immunotherapy
Maria Wendt, PhD, Head of Science, Genedata

Bispecific Antibodies for Cancer Immunotherapy Session
Thursday, May 4 | 15:20 - 15:50

Bi- and multi-specific antibodies, Ab-cytokine fusion proteins, non-Ig scaffolds, chimeric antigen receptors (CARs), engineered TCRs and TCR-based bispecific constructs can provide significant advantages for use in cancer immunotherapy. However, as highly engineered molecules they pose new design, engineering, cloning, expression, purification, and analytics challenges. Genedata Biologics enables the automated design, screening, production, and testing of large panels of these candidate therapeutic molecules and includes built-in tools for developability and manufacturability assessments.

Identification and Quantitation of DuoBody® Bispecific IgG1 Using Mass Spectrometry and Automated Data Processing and Analysis Workflow
Ewald van den Bremer, PhD, Senior Scientist, Genmab

Biophysical Analysis of Biotherapeutics Session
Thursday, May 4 | 09:35 - 10:05

The characterization of bispecific antibodies (BsAbs) by mass spectrometry (MS) offers several advantages over traditional chromatographic techniques (e.g.  HIC, CEX). MS provides unambiguous identification and relevant quantitative information, and combined with automated data processing and analysis, it can be employed in a high-throughput environment. We present a software solution and the related workflows that enabled us to accelerate BsAb research batch characterization and release, achieving high quality results and significant time and cost savings.

Recommended Poster Presentation

Poster Session A
May 1 - 2, 2017

High-throughput Screening, Design, Production, and Evaluation of Bispecific Antibodies
Andrew Lynch, PhD, Scientific Consultant, Genedata

New Platform for Antibody Developability and Manufacturability Assessment
Jolyon Terragni, PhD, Scientific Consultant, Genedata

Automated Data Processing for Quality Monitoring of Biotherapeutics by Multi-attribute Methods (MAMs)
David Bush, PhD, Scientific Account Manager, Genedata


Poster Session B
May 3 - 4, 2017

Generation, Design and Evaluation of TCR-, TCR mimetic- and CAR-based Therapeutics for Cancer Immunotherapy
Maria Wendt, PhD, Head of Science, Genedata

Evaluation of Large Panels of Bispecific Antibodies using Surface Plasmon Resonance
Lope Florez, PhD, Head of Scientific Account Management, Genedata

Automated Workflow for Host Cell Protein Monitoring by Mass Spectrometry: From Raw Data to Final Report
Cassandra Wigmore, Business Account Manager, Genedata