April 23–25, 2018
Amsterdam, the Netherlands
Meet Genedata experts at the BioProcess International European Summit in Amsterdam, the Netherlands.
Don't miss the opportunity to see how the Genedata Bioprocess® workflow system improves process quality and efficiency of large-molecule development and CMC activities by streamlining and automating complex workflows in cell line development, upstream and downstream process development, drug formulation, and analytical development.
In addition, Genedata scientists from Selector will be attending the Viral Safety and Raw Materials stream to discuss the use of our software in analyzing and managing NGS data for adventitious agent detection in biological production.
High Throughput Cell Line and Scale-down Upstream Process Screening
Christoph Freiberg, Ph.D., Senior Scientific Consultant, Bioprocess, Genedata
We present use cases demonstrating the automation of the development and assessment of mammalian cell lines and related upstream processes in high throughput, including seeding, selection, passaging, cryo-conservation, as well as batch and fed-batch processing and data analysis. We show how the full history of all clones can be tracked - from initial transfection all the way to their evaluation in bioreactor runs - and how this information can be combined with product quality and analytics data. These automation approaches include the integration with instruments, such as pipetting robots, colony pickers, bioreactors and bioanalyzers and deal with cell line and process development for both antibodies (IgGs, novel formats) as well as therapeutic proteins (e.g., fusion proteins).
Cell Culture & Upstream Processing
Monday, April 23 | 10:40–11:00
A Platform Approach to Decrease Developability & Manufacturability Risks of Biologics Molecules
High-throughput Screening for Best Manufacturing of Cell Lines using Scale-down Models