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Developing a Generic HT Assay for DuoBody® Characterization

Using Genedata Expressionist®, scientists at Genmab established an automated MS-based high-throughput assay that provides qualitative and quantitative information on a DuoBody® bsAb preparation in a fraction of the time and effort required by conventional CEX-based methods. Compared to the CEX-based process, the time required for data acquisition and processing was reduced by 95% and the number of person hours dedicated to data processing was reduced by 70%.