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Digitalization of AAV Bioprocess Development

BPI 2022, Vienna
May 17, 2022

We present an E2E platform that supports the entire bioprocess development workflow starting from registering a therapeutic virus, tracking the plasmids and host cell lines used for AAV production, and managing the process steps of plasmid purification, transfection, and production, as well as the purification of the viral vectors. All analytical data coming from various instruments are automatically associated to the intermediates and products of each process step. The design of this novel platform enables significant efficiency and quality gains in process development.

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