The MorphoSys pipeline is based on a combination of strong business partnerships and proprietary development activities. MorphoSys has partnered with major biopharmaceutical companies including Astellas, Bayer, Merck & Co., Boehringer Ingelheim, Novartis, Janssen, Pfizer, Daiichi Sankyo, F. Hoffmann-La Roche, and Shionogi. Using MorphoSys’ proprietary synthetic antibody libraries and their phage display screening technologies HuCAL, Ylanthia and Slonomics, MorphoSys enables faster, more flexible and, ultimately, better-quality access to drug candidates.
The rapid growth of MorphoSys has led to a significant increase in molecule and sample throughput, which has made it challenging to capture, process, and interpret the huge amount of resulting R&D data. “The scale and throughput of our operations necessitated the use of an enterprise workflow platform to manage and streamline the growing number of our discovery programs,” said Dr. Markus Enzelberger, Chief Scientific Officer at MorphoSys.
To cope with this data avalanche, MorphoSys decided to implement a corporate workflow platform as a “data backbone” to capture and process all data generated by their R&D programs. The goal of the new system was to make MorphoSys’ sophisticated R&D processes more efficient and to facilitate handovers between various R&D teams and functions, including screening, molecular biology, engineering, expression, purification and analytics. The new system also needed to be able to handle the increasing amount of data and samples produced by external partners, such as CROs, which had to be integrated into MorphoSys’ R&D process.
Flexibility and scalability of the new solution was of utmost importance. “Our biopharma R&D operations required an integrated and scalable informatics infrastructure that can be tailored to support our biologics discovery processes,” continued Dr. Enzelberger. MorphoSys required a solution that could be flexibly adapted to future R&D processes.