Genedata Selector® is an end-to-end enterprise software designed to simplify and streamline the analysis of NGS-based cell line development and biosafety workflows in a GMP environment. It provides a single source of truth, empowering scientists to integrate, analyze, and share all project-related data for improved decision making. Automate all NGS-based workflows today.
Selected Applications
Accurate and Efficient NGS-Based Biosafety Testing
Automate data processing, analysis, and reporting to accelerate data-informed decision-making for faster and safer biotherapeutics development. The end-to-end solution for NGS detects adventitious agents, providing an unbiased approach to assess the presence of all organisms, suitable for testing starting materials, unprocessed bulk harvest, and the final product.
Identify detrimental mutations early and replace lengthy assays with innovative techniques for immediate results. For example, single-cell RNA-Seq allows early detection of heterogeneous cell banks and undesired products to avoid future high costs.
Integrate into cGMP environments to provide 21 CFR part 11-compliant reports to regulatory affairs. The software provides full documentation, controlled user access, and timestamped transaction records for compliant operation.
Learn MoreEffective Cell Line Development
Streamline the analysis and interpretation of NGS data for cell line development applications, including confirming clone identity, refining host cell lines, and verifying product integrity, stability, and purity.
Genedata supports comprehensive annotation of proprietary genomes for public domain data integration, molecular and signaling pathways, splice variants, microRNAs, mutations, and CNVs. Assess cell line heterogeneity and ensure desired attributes using Single-cell RNA Sequencing (scRNA-seq) with sophisticated visualizations and automated reports.
The platform supports you to predict quality-controlled guide RNAs for CRISPR-based targeted engineering, ensuring a secure environment with reduced IP risk and providing valuable information such as gRNA specificity scores and high-quality primer sequences.
Bioprocess Optimization
Accelerate your analysis and interpretation of omics data for bioprocess development by streamlining data processing workflows and enabling efficient decision-making to bring biotherapeutics to market faster. Visualize omics data over different timepoints or experimental conditions, and monitor pathways to identify potential engineering targets such as bottlenecks in cellular machinery.
Genedata identifies cell variants throughout bioprocess development using DNA-, RNA-seq, or mutation profiling to rapidly determine product sequence integrity and accelerate decisions from small to large scale processes. It therefore detects unstable clones early to prevent the development of heterogeneous cell banks and undesired products, identifying critical mutations or variations in cell populations with single-cell RNA sequencing.
Learn MoreCell and Gene Therapy Development
Facilitate the analysis and interpretation of NGS data for cell and gene therapy development, focusing on Critical Quality Attribute (CQA) assessment to confirm identity, biosafety, and potency, accelerating the delivery of safe and effective therapies.
Genedata automates and standardize NGS-based cell and gene therapy assays with out-of-the-box support for safety assays, sequence characterization, and potency assessment. Detect adventitious agents like mycoplasma throughout the development process to ensure mycoplasma-free cell and gene therapies. Streamline decision-making with single-cell RNA sequencing data analyses, using informative and interactive data displays.
Industrial Biotechnology
Do you want to leverage NGS-based production strain development and process optimization to collect genotype-phenotype data and phenotypically characterize a large number of strains? Genedata tracks data and decisions to provide a molecular history of the production strain, simplifying reporting to regulatory agencies and accelerating time-to-market with workflows for strain stability testing and safety assessment.
By supporting WGS metagenomics annotation to analyze metagenome and meta-transcriptome pathways, and manage operational taxonomic units (OTUs) for new signatures, enabling lead- or indicator-strain identification and process optimization, Genedata enables you to go beyond 16S RNA-based taxonomy screening to characterize and reconstruct molecular mechanisms on a microbial community level, and ensures genomic data mining for developing new antibiotics and antifungals for individualized treatment and the prevention of resistance through biofilm, microbiome sequencing, and secondary metabolite screening.
Learn MoreAgricultural Science
Genedata supports crop improvement and plant breeding initiatives by leveraging NGS and other omics data for mutation analysis, metabolic pathway analysis, and genotype-phenotype relationship interpretation. Enable your cross-omics data processing and analysis of genotype-phenotype relationships for numerous crop and vegetable genome sequences, facilitating comparative genomics of sequence, mutation, protein function, regulation, and pathway activity levels of plants, microbes, and microbiomes. Link central genome management for plants and germplasm mutation profiling with sequence information of breeding markers and phenotype data for marker-assisted breeding and gene editing.
The platform facilitates whole-genome comparisons from mutations to gene functions and pathways to identify potential targets in crop protection, supporting compound-specific mode of action (MoA) analysis and screening of all genomes to predict efficacy for other strains and organisms.
Learn MoreDiscover The Software
Explorer for Collaborative Genome Data Management
Organize complex genome information by managing public and proprietary genome data, and discover genotype–phenotype relationships across genomes, from harmonization of genomic data and refinement of gene model annotation to full functional reconstruction. Genedata simplifies access to genome information by browsing through genome sequences and zooming in on the gene of interest to investigate variants on nucleotide and protein levels.
In addition, the platform enhances collaboration and shares knowledge through interactive communication via notifications and shared views in the software. With Genedata, project teams can easily share knowledge with other teams or partnering organizations.
Learn MoreProcessor for Reproducible Results
Customize workflows for a variety of analyses, including DNA-seq, RNA-seq, single-cell RNA-seq, and metagenomics. Integrated into Genedata, Processor provides a comprehensive set of up-to-date bioinformatics tools, with the ability to incorporate newly released tools through APIs.
The platform automate your NGS workflows, enabling standardized, automated processing of raw NGS data independent of the sequencing technology or instrument used, providing comprehensive raw data quality control, built-in business logic, sanity checks of workflows and workflow activity, combined with interactive results visualization.
Learn MoreAnalyst for In-Depth Analysis and Interactive Visualizations
Enable sophisticated statistical analysis and interactive visualization of complex data with a secure, scalable data mining solution that integrates seamlessly into existing research IT environments using a rich toolbox of APIs. Genedata, facilitates interactive visualization for simplified data interpretation, supporting integration from various file formats, making it accessible for researchers and biostatisticians. Easily utilize advanced interactive data mapping, analysis, mining, and visualization with a range of statistical applications, including t-Test, ANOVA, linear models, PCA, PLS, and more.
Learn MoreTracker for End-to-End Sample Tracking
Manage and track sample meta-information efficiently through an analysis pipeline with configurable, intuitive user interfaces for step-by-step data entry. Filter, search, and display sample information in lists, and visualize data with intuitive graphs, making it easy to store and share results within your project team. Genedata ensures comprehensive sample history tracking and audit reports with built-in GMP-required functionalities, complying with FDA’s 21 CFR Part 11 regulation to maintain data authenticity, integrity, and confidentiality.
Learn MoreSimplify Complex Analyses and Reporting with Playbooks
Guide users through data registration with wizard-based Playbooks tailored to your laboratory workflows, combining sample tracking with automated data processing and report generation. Genedata streamlines and automate NGS data analysis, increasing scalability through standardized data processing with verified, customizable, and lockable workflows. Save time with automatically generated standard reports, customizable to include all relevant information for your laboratory, workflow, and assay.
Learn MoreUse Genedata Selector to:
Automate Routine Workflows
The inbuilt user-friendly and easy-to-use Playbooks automate routine workflows increasing standardization, transparency, and throughput from data entry and processing to report generation. This prevents errors due to manual data handling.
Accelerate Decision-Making
Streamline decision-making based on actionable scientific insights. Genedata Selector not only accelerates standardized data processing and analysis with automated workflows but also accelerates results sharing, decisions, and project documentation within the team.
Protect Intellectual Property
With Genedata Selector, there is no need to send out proprietary host cell line sequence information to external partners. All related data can be analyzed by scientists inhouse against the proprietary host cell line genome – reducing the IP risk of sending genome information to service providers or obtaining divergent results by using public domain reference genomes.
Increase Transparency & Simplify Reporting
Prepare for regulatory submissions with Genedata Selector. This software enables full automation and ensures record traceability from sample registration to report generation in a validated environment, simplifying assay development and execution.