バイオ医薬品の創薬

Automating Cell Therapy R&D

Streamline cell therapy R&D with purpose-built tools for designing and evaluating large panels of cell-based therapeutic modalities for novel immunotherapies.

By integrating directly with laboratory equipment, Genedata Biologics fully automates sample handling and testing procedures. The platform supports screening and engineering of diverse formats, including chimeric antigen receptor T cells (CAR-T), T cell receptor technologies (TCRs), and antibody TCR-mimetics (e.g., dsTCR, TCR-scFv, bispecific TCRs).

Streamlining Gene Therapy Workflows

Accelerate gene therapy R&D by supporting the entire workflow, from serotype optimization and viral vector design to virus packaging, purification, and testing. 

Genedata Biologics tracks all samples and associated data, including custom vectors, packaging plasmids, cell lysates, purified virus batches and their sequences, titers, and assay results such as empty-to-full capsid ratios. The platform also supports diverse viral delivery systems, including AAV, adenovirus, and retrovirus vectors.

Enhancing ADC Discovery and Development

Register and track large panels of Antibody-Drug Conjugates (ADC) candidates while managing linker and payload data (e.g., cytotoxic small molecules) in a single integrated platform that combines analytics and functional assay results.

Genedata Biologics streamlines the entire ADC discovery process — from antibody screening and engineering to expression, purification, drug conjugation, and reporting of ADC metrics such as DAR, drug distribution, and homogeneity.

Accelerating Vaccine Development

Streamline novel vaccine discovery by improving efficiency, speeding up testing, simplifying production, ensuring quality, and reducing costs.

Genedata Biologics supports emerging vaccine technologies such as synthetic self-amplifying mRNA, enabling faster development through cell-free processes and rapid antigen production, alongside traditional vaccine R&D.

Transforming RNA Therapeutics

Revolutionize the end-to-end design and development of RNA therapeutics and vaccines with a platform that registers, tests, and evaluates nucleic acid-based candidates at every stage, covering RNA/DNA optimization for effectiveness and stability.

Paired with advanced screening workflows for formulation development and functional characterization, Genedata Biologics delivers a critical data infrastructure that enables faster RNA therapeutic development.

Streamlining B-Cell-Derived Therapeutic Antibody Discovery

Facilitate B cell-derived therapeutic antibody R&D by streamlining every stage of the complex B cell-based discovery process. Genedata Biologics tracks animal and immunization data and registers molecules, samples, quality control, and functional assay results in a centralized platform.

ELISA, FACS, and SPR experiments are managed within the platform. When combined with V-region sequencing data, this enables integrated analysis of molecular sequences and functional performance. 
 

Mitigating Developability Risks

Minimize developability and manufacturability risks by systematically assessing each candidate’s risk profile and critical quality attributes (CQA) to identify the most promising ones for development. 

Genedata Biologics evaluates manufacturability by flagging potential issues during expression and purification and assessing properties that affect molecular robustness at the biophysical and biochemical level.

Protein Engineering and Optimization

The software enables efficient engineering of virtually any protein format and supports the generation of combinatorial libraries from known molecular building blocks. Built-in tools facilitate the design and optimization of IgGs and complex next-generation antibody formats, such as bi- and multi-specifics.

It supports simultaneous optimization of candidate properties — including binding affinity, cross-reactivity, stability, expressibility, and other critical attributes. Advanced tools for affinity maturation, site-directed mutagenesis, germlining, humanization, reformatting, and isotype switching enable rapid and reliable generation of optimized protein variants.

Protein Production and Quality Control

To increase efficiency across the entire protein production process, the software tracks and validates each step, from initial protein definition to final, fully characterized high-quality samples. This includes all expression and purification batches, as well as vector and cell line batches.
 
Analytical characterization and QC data — including LC-MS, SEC, HIC, endotoxin levels, glycosylation profiles, and in vivo assay results — are aggregated and directly linked to their respective samples. Certificates of Analysis (CoAs) and other relevant reports are automatically generated using built-in tools.

Improving R&D Efficiency with Unified Task Management

The software enhances operational efficiency and oversight of R&D activities by supporting the full lifecycle of task scheduling. It manages request submission and tracking from initiation through completion, facilitates intra- and intergroup communication, and centrally documents request progress in real time.

Centralized Tracking and Lifecycle Management

The software provides a fully integrated solution for managing samples — from cell banks and plasmids to proteins and complex mixtures. It centralizes inventory control, sample tracking, and workflow automation, delivering complete visibility into each sample’s lifecycle.

By linking samples directly to analytics, assay results, and QC data, the platform enables end-to-end traceability. Automated storage management, real-time occupancy dashboards, and barcode-based identification streamline handling, while audit-ready logs and version histories support regulatory compliance.