ポスター：LC/MSを用いたMulti-Attribute Method（MAM）の導入を効率化するEnd-to-endソフトウェアプラットフォーム

Bioprocessing Summit, Boston, MA, USA
August 19, 2024

We present an integrated software solution that covers the entire MAM workflow, featuring extracted ion chromatogram (XIC) based quality monitoring, automated results review, and an enhanced new peak detection (NPD) component for a scalable end-to-end MAM implementation. We demonstrate that combining an untargeted peptide-mapping-based approach and a targeted XIC-based approach streamlined the accurate identification of new peaks and the efficient monitoring of critical quality attributes while reducing the number of false positives.