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Festival of Biologics

Basel, Switzerland
November 9–11, 2021

Meet Genedata experts at the Festival of Biologics.

Don't miss the opportunity to see how Genedata solutions efficiently support the whole biopharmaceutical R&D workflow, including screening and protein engineering, expression and purification, characterization and analysis of protein therapeutics, cell line design and development, bioprocess optimization, stratification of clinical trial subjects, and quality control of biologicals.

For more information about Genedata solutions or to set up a meeting, please contact info(at)genedata.com.

Recommended Oral Presentations

Accelerating Novel Immunotherapeutic Modality Discovery through Digitalization    
Sebastian Schlicker, Head, Operations, Biologics, Genedata 
Wednesday, November 10, 2021 | 9:30–9:55 am

The advent of novel immunotherapeutic modalities, including next-generation antibodies, cell & gene therapies and RNAs, has resulted in massive amounts of complex R&D data needing to be systematically structured and interpreted. We present case studies showing how biopharma and biotech organizations digitalize and automate their bi- and multi-specific antibodies, AAV, CAR-T, and TCR-T workflows and how they leverage having  full traceability and data integrity for data sciences and ML approaches.

Learn more

Keeping Pace with the Increasing Complexity of Multispecific Biotherapeutics: Bioanalysis of Mispairing & In-Depth Peptide Mapping Analysis    
Soraya Hölper, Ph.D., Project Lead for Portfolio and Strategy, Sanofi  
Wednesday, November 10, 2021 | 4:40 pm

This presentation will focus on:

  • Challenges of multispecific biotherapeutic analytics
  • Analytical strategies to characterize mispairing
  • Identification of labile hot spots to improve chemical stability

High Throughput and Format-Agnostic Mispairing Assay for Multispecific Antibodies using Intact Mass Spectrometry    
Jennifer Jung, Ph.D., Lab Head Mass Spectrometry, Sanofi  
Wednesday, November 10, 2021 | 5:40 pm

We developed a high throughput mispairing assay using intact mass spectrometry. This assay can support screening campaigns and detect mispaired species of ~1000 molecules in three weeks by one person. As proof of concept the assay was used to detect and perform relative quantification of mispaired species in trispecific antibodies.

Recommended Panel Discussion

Accelerating Biopharma R&D: Merging Automation & Data Management to Enable Collaboration and Innovation    
Moderated by Jana Hersch, Ph.D., Scientific Consultant, Biologics, Genedata
Wednesday, November 10, 2021 | 10:20–10:35 am

Panelists
Soraya Hölper, Lab Head Mass Spectrometry, Sanofi
Björn Hüber, Team Leader Data Management, Novartis
Alexander Jung, Head of Digitalization Biologicals Development CMC, Boehringer Ingelheim
Uwe Wittenberg, Director Research Informatics, Merck
Ezio Bonvini, Chief Scientific Officer, MacroGenics
Markus Enzelberger, Partner, Versant Ventures

  • Digitalization strategies – challenges & successes
  • Automation - instrument integration, workflow and process automation
  • Enabling collaboration & innovation through digitalization
  • Future trends and AI approaches

Learn more

Recommended Poster Presentations

Industrializing Immuno-Oncology Therapeutic Discovery Platforms
Jana Hersch, Ph.D., Scientific Consultant, Biologics, Genedata

End-to-End Workflow Platform for Integrated Biopharmaceutical Development
Eric Abellan, Business Account Manager, Biologics, Genedata

Streamlining & Increasing the Efficiency of Large-Molecule Discovery Workflows
Stefan Jehle, Ph.D., Head of Sales, Europe, Biologics, Genedata

A Platform Approach to Manage the Automated Production of Viral Vectors for Cell and Gene Therapy
Carl Bruder, Ph.D., Scientific Consultant, Biologics, Genedata

A Fully Automated Data Workflow for MS-Based Identification Testing of Therapeutic Oligonucleotides Suitable for Use in GMP Environments
Arnd Brandenburg, Ph.D., Scientific Consultant, Expressionist, Genedata

Robust and Accurate CQA Monitoring Using an Enterprise Software Platform Providing Flexible Solutions for the Multi-Attribute Method (MAM)
Claudio Schmid, Ph.D., Business Account Manager, Expressionist, Genedata

Automating Assay Data Analysis Along the Discovery Pipeline
Isabel Kolinko, Ph.D., Scientific Consultant, Screener, Genedata