Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants.
Freiberg C, Fischer HP, Brunner NA.
PMID: 15673760 [PubMed - indexed for MEDLINE]
Transcript Analysis of Early Nodulation Events in Medicago truncatula
Dasharath Prasad Lohar , Natalya Sharopova , Gabriella Endre , Silvia Peñuela , Deborah Samac , Christopher Town , Kevin A.T. Silverstein , and Kathryn A. VandenBosch
2005; 10.1104/pp.105.070326
Transcriptome analysis and physical mapping of barley genes in wheat-barley chromosome addition lines
Cho S, Garvin DF, Muehlbauer GJ.
Genetics. 2005 Dec 1; PMID: 16322516 [PubMed - as supplied by publisher]
Towards quantitative biology: Integration of biological information to elucidate disease pathways and to guide drug discovery.
Fischer HP
Biotechnol Annu Rev. 2005;11:1-68. PMID: 16216773 [PubMed - in process]
Frequency of blood CX3CR1-positive natural killer cells correlates with disease activity in multiple sclerosis patients
Carmen Infante-Duarte, Alexandra Weber, Jörn Krätzschmar, Timour Prozorovski, Susan Pikol, Isabell Hamann, Judith Bellmann-Strobl, Orhan Aktas, Jan Dörr, Jens Wuerfel, Claus-Steffen Stürzebecher, and Frauke Zipp
FASEB J, Sep 2005; 10.1096/fj.05-3832fje
Myocardial Insulin-Like Growth Factor-I Gene Expression During Recovery From Heart Failure After Combined Left Ventricular Assist Device and Clenbuterol Therapy
Paul J. R. Barton, Leanne E. Felkin, Emma J. Birks, Martin E. Cullen, Nicholas R. Banner, Suzanne Grindle, Jennifer L. Hall, Leslie W. Miller, and Magdi H. Yacoub
CARDIAC TRANSPLANTATION AND SURGERY FOR CONGESTIVE HEART FAILURE, Circulation, Aug 2005; 112: 46 - 50.
Gene Profiling Changes in Cytoskeletal Proteins During Clinical Recovery After Left Ventricular–Assist Device Support
Emma J. Birks, Jennifer L. Hall, Paul J.R. Barton, Suzanne Grindle, Najma Latif, James P. Hardy, James E. Rider, Nicholas R. Banner, Asghar Khaghani, Leslie W. Miller, and Magdi H. Yacoub
CARDIAC TRANSPLANTATION AND SURGERY FOR CONGESTIVE HEART FAILURE, Circulation, Aug 2005; 112: 57 - 64.
Functional Genomics in Antibacterial Drug Discovery
C. Freiberg, H. Brotz-Oesterhelt
Drug Discovery Today. 2005 Jul 1:10(13):927-35
Gene Expression Profiles of Blumeria graminis Indicate Dynamic Changes to Primary Metabolism during Development of an Obligate Biotrophic Pathogen
Maike Both, Michael Csukai, Michael P.H. Stumpf, and Pietro D. Spanu
PLANT CELL, Jun 2005; 10.1105/tpc.105.032631
Integrative Genomic, Transcriptional, and Proteomic Diversity in Natural Isolates of the Human Pathogen Burkholderia pseudomallei
Keli Ou, Catherine Ong, Shze Yung Koh, Fiona Rodrigues, Siew Hoon Sim, Daniel Wong, Chia Huey Ooi, Kim Chong Ng, Hiroyuki Jikuya, Chin Chin Yau, Sou Yen Soon, Djohan Kesuma, May Ann Lee, and Patrick Tan
J. Bacteriol., Jun 2005; 187: 4276 - 4285
Gene expression profiles of breast cancer obtained from core cut biopsies before neoadjuvant docetaxel, doxorubicin, and cyclophosphamide chemotherapy correlate with routine prognostic markers and could be used to identify predictive signatures
A. Rody, T. Karn, M. Munnes, G. von Minckwitz, S. Loibl, C. Solbach, U. Holtrich and M. Kaufmann
Vol 23, No 16S (June 1 Supplement), 2005: 646, © 2005 American Society of Clinical Oncology
Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes
Bubnoff A, Peiffer DA, Blitz IL, Hayata T, Ogata S, Zeng Q,
Developmental Biology (2005) May 15;2812(2):210 - 26.
From Targets to Leads: The importance of advanced data analysis for decision support in drug discovery
Hans Peter Fischer, Stephan Heyse
Current Opinion in Drug Discovery & Development Vol. 8, No. 3, 2005, pp. 334 - 336
Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease
Raymond Tabibiazar, Roger A. Wagner, Euan A. Ashley, Jennifer Y. King, Rossella Ferrara, Joshua M. Spin, David A. Sanan, Balasubramanian Narasimhan, Robert Tibshirani, Philip S. Tsao, Bradley Efron, and Thomas Quertermous
Physiol Genomics (2005)
Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells
D. Viemann, A. Strey, A. Janning, K. Jurk, K. Klimmek, T. Vogl, K. Hirono, F. Ichida, D. Foell, B. Kehrel, V. Gerke, C. Sorg, J. Roth
Blood, 2005, Apr 1;105(7), pp 2955-2962
Global expression of prophage genes in Escherichia coli O157:H7 strain EDL933 in response to Norfloxacin
S. Herold, J. Siebert, A. Huber, H. Schmidt
Antimicrobial Agents and Chemotherapy, 2005, March, Vol. 49, No. 3, pp. 931-944
Dynamic response of plant genome to ultraviolet radiation and other genotoxic stresses
J. Molinier, E. J. Oakeley, O. Niederhauser, I. Kovalchuk, B. Hohn
Mutation Research, 2005, Volume 571, Issues 1-2, pp 235-247
The impact of sophisticated data analysis on the drug discovery process
A. Kaul Business Briefing: Future Drug Discovery 2005
Click on the link to open the PDF file:
BB_2005.pdf (1MB)
NFκB-dependent downregulation of TRAF proteins contributes to IL-1-mediated enhancement UVB-induced apoptosis
B. Pöppelmann, K. Klimmek, E. Strozyk, R. Voss, T. Schwarz, D. Kulms
Journal of Biological Chemistry, 2005, February, in press.