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Publication: Large-scale, Comprehensive Quality Control and Analysis of High-Throughput Screening DataEuropean BioPharmaceutical Review, Spring 2003
High-throughput screening (HTS) is used to search a vast area of the chemical universe for bioactive compounds and provides biological data on different targets from standardized, sensitive and well-controlled experiments for hundreds of thousands of compounds. However, this wealth of information is rarely exploited to its fullest extent and expensive resources are therefore often wasted. In order to address this problem, intelligent methods and software to process and combine results from different HTS screens, secondary tests and lead profiling experiments are being developed.
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