Systematically measuring bioactivity of large, diverse compound collections (tens of thousands to millions of compounds), High Throughput Screening (HTS) and ultra-High Throughput Screening (uHTS) are crucial starting points in drug discovery. In order to identify hits and promising structure clusters, large data volumes need to be accurately and rapidly processed, reviewed, combined and filtered.
Genedata Screener features scalable processing and interactive review capabilities for up to millions of datapoints per experiment and dedicated management of screening data from hundreds of assays. Automated processing methods, systematic quality control functions and comprehensive analysis workflows allow for shorter experiment cycles and better usage of data and information, accelerating the lead discovery process.
Benefits of Screener's application to (u) HTS
- Rapid quality control and quality assurance of plate-based data from entire campaigns in a single session
- Dose-response curve fitting and quality control of secondary screens, yielding precise IC50s for tens of thousands of compounds in a single session
- Efficient compound filtering and hit list generation by multiple criteria, based on assay results
- Comprehensive data management across the corporation
- Automated processing and interactive summary review at all stages of the process, eliminating the tedious manual review of individual plates and compounds
Read more about Genedata Screener.