Genedata Phylosopher®: Biotech & Life Science

MetaLead for Metabolic Engineering: Developed for applications in both prokaryotic and eukaryotic systems, the Phylosopher MetaLead solution provides insights into metabolite and protein (over)production. The analysis of transcriptomics, proteomics and metabolomics data elucidates the complex interaction between the organism, its metabolism, the culture conditions and also the transcriptional networks that affect biochemical pathways. This thorough investigation of the biology behind metabolic capabilities of production strains paves the way to increased metabolite and protein production.

AgroLead for Agrobiological Research: The biochemical networks behind plant development, growth, and production are the focus of Phylosopher AgroLead. Specialized tools support testing hypotheses, identifying and validating markers in breeding research as well as developing assays and performing mechanism-of-action efficacy studies for crop protection applications. Transcriptomics, proteomics and metabolomics data analysis investigates the complex interaction between the plant, its metabolism and environment. Exploiting the biology behind agronomic traits at the physiological, biochemical, and molecular level is a key step towards better crop protection and increased crop production.

PathoLead for Anti-Infectives Research: The Phylosopher PathoLead solution focuses on target, assay and compound information that enables the interpretation and leverage of omics data in the context of the antibiotics discovery and development process. PathoLead integrates comprehensive pathogen biology information, ranging from complete pathogen genomes, proteomes and metabolomes to high quality functional information. PathoLead provides tools for testing hypotheses about newly discovered pathways; algorithms for identifying, validating and ranking target candidates; and modules to prioritize the development of novel potent drug classes to cure infectious diseases.

SysLead for Systems Biology: Phylosopher`s Systems Biology solution SysLead features a database and computing infrastructure capable of integrating data from large organizational frameworks with different research groups, locations, technologies and analysis techniques. SysLead particularly bridges the gap between experimental data (“wet labs”) and computer-generated modelling data (“dry labs”). The SysLead data processing and integration pipeline covers the entire process from automated quality assessment of the experimental data all the way to interfaces connecting to pathway modelling software. The central database facilitates the exchange of experimental data as well as results based on in silico modelling.