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Genedata Expressionist®: Metabolomics

MS and NMR based metabolomics

Expressionist standardizes and automates high-throughput mass spectrometry and NMR analysis tasks. The platform guarantees reliable and reproducible results from metabolite profiling data.

Expressionist supports metabolomics with the modules Refiner MS and Analyst. Refiner MS performs objective technology-specific quality assessments, process monitoring and uploading of MS processed data to the database. There it can be accessed by the Analyst module for integrated analysis and interpretation. Based on the large number of different NMR setups and data formats we recommend data pre-processing with specialized tools and further integrated data analysis and interpretation in Analyst.



Metabolomics process supported by Expressionist:

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Measurement of samples using mass spectrometry generates raw data.
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The Refiner MS module uploads raw data and performs pre-processing and QC. The created quality-controlled processed data are stored in the database.
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The Analyst module loads and analyzes the data from the database. Statistical analysis reveals lists of significantly changing peaks.
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Identification of metabolites, annotation of peaks and spectra, interpretation
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Alternatively, samples are measured using NMR technology. Pre-processed data are loaded into Analyst for statistical analysis. Additional experimental data can be integrated for more biological insight. Mapping the list of putative biomarkers to pathways can give hints to biological systems for further investigation.

Read more on integrated data analysis and the integration of R scripts, third party pathway providers and other benefits of the open Expressionist software architecture.


Click for a list of supported technologies.


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