2007

The peer-reviewed publications listed below each acknowledge support of Genedata

Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1-derived peptide Ac1-25: Carsten Lange, Diane Starrett, Julia Goetsch, Volker Gerke, and Ursula Rescher
J. Leukoc. Biol. published 12 September 2007, 10.1189/jlb.0307158

Proteomic characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling: Sebastian Wiese, Thomas Gronemeyer, Rob Ofman, Markus Kunze, Claudia P. Grou, Jose A. Almeida, Martin Eisenacher, Christian Stephan, Heiko Hayen, Lukas Schollenberger, Thomas Korosec, Hans R. Waterham, Wolfgang Schliebs, Ralf Erdmann, Johannes Berger, Helmut E. Meyer, Wilhelm Just, Jorge E. Azevedo, Ronald J. A. Wanders, and Bettina Warscheid
Mol. Cell. Proteomics. published 2 September 2007, 10.1074/mcp.M700169-MCP200

Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease: Wei Zheng, Janak Padia, Daniel J. Urban, Ajit Jadhav, Ozlem Goker-Alpan, Anton Simeonov, Ehud Goldin, Douglas Auld, Mary E. LaMarca, James Inglese, Christopher P. Austin, and Ellen Sidransky
PNAS. 2007; 104(32): p. 13192-13197 Open Access

Acute Hepatotoxicity: A Predictive Model Based on Focused Illumina Microarrays: Nadine Zidek, Juergen Hellmann, Peter-Juergen Kramer, and Philip G. Hewitt
Toxicol. Sci. 2007; 99(1): p. 289-302

Human endometriosis is associated with plasma cells and overexpression of B lymphocyte stimulator: Aniko Hever, Richard B. Roth, Peter Hevezi, Maria E. Marin, Jose A. Acosta, Hector Acosta, Jose Rojas, Rosa Herrera, Dimitri Grigoriadis, Evan White, Paul J. Conlon, Richard A. Maki, and Albert Zlotnik
PNAS. published 17 July 2007, 10.1073/pnas.0703451104

Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation: Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky
Biol Reprod, Jul 2007; 77: 165 - 171

A Transgenic Mouse Model of Plasma Cell Malignancy Shows Phenotypic, Cytogenetic, and Gene Expression Heterogeneity Similar to Human Multiple Myeloma: Kristin L.M. Boylan, Mary A. Gosse, Sarah E. Staggs, Siegfried Janz, Suzanne Grindle, Geoffrey S. Kansas, and Brian G. Van Ness
Cancer Res., May 2007; 67: 4069 - 4078

Carcinogen-Specific Gene Expression Profiles in Short-term Treated Eker and Wild-type Rats Indicative of Pathways Involved in Renal Tumorigenesis: Kerstin Stemmer, Heidrun Ellinger-Ziegelbauer, Hans-Juergen Ahr, and Daniel R. Dietrich
Cancer Res., May 2007; 67: 4052 - 4068

Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes: Jan Ehrchen, Lars Steinmüller, Katarzyna Barczyk, Klaus Tenbrock, Wolfgang Nacken, Martin Eisenacher, Ursula Nordhues, Clemens Sorg, Cord Sunderkötter, and Johannes Roth
Blood, Feb 2007; 109: 1265 - 1274

Novel Insights into Lung Transplant Rejection by Microarray Analysis: Jeffrey D. Lande, Jagadish Patil, Na Li, Todd R. Berryman, Richard A. King, and Marshall I. Hertz
Proceedings of the ATS, Jan 2007; 4: 44 - 51

Modulation of Gene Expression and Cytoskeletal Dynamics by the Amyloid Precursor Protein Intracellular Domain (AICD): Thorsten Müller, Caoimhin G. Concannon, Manus W. Ward, Ciara M. Walsh, Anca L. Tirniceriu, Florian Tribl, Donat Kögel, Jochen H.M. Prehn, and Rupert Egensperger
Mol. Biol. Cell, Jan 2007; 18: 201 - 210

Proteomic Signature Corresponding to the Response to Gefitinib (Iressa, ZD1839), an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma: Tetsuya Okano, Tadashi Kondo, Kiyonaga Fujii, Toshihide Nishimura, Toshimi Takano, Yuichiro Ohe, Koji Tsuta, Yoshihiro Matsuno, Akihiko Gemma, Harbumi Kato, Shoji Kudoh, and Setsuo Hirohashi
Clin. Cancer Res., Feb 2007; 13: 799 - 805

Poor Outcome in Estrogen Receptor–Positive Breast Cancers Predicted by Loss of Plexin B1: Achim Rody, Uwe Holtrich, Regine Gaetje, Mathias Gehrmann, Knut Engels, Gunter von Minckwitz, Sibylle Loibl, Raihanatou Diallo-Danebrock, Eugen Ruckhäberle, Dirk Metzler, Andre Ahr, Christine Solbach, Thomas Karn, and Manfred Kaufmann
Clin. Cancer Res., Feb 2007; 13: 1115 - 1122

Differential Gene Expression among the Proximal Segments of the Rat Epididymis Is Lost after Efferent Duct Ligation: Terry T. Turner, Daniel S. Johnston, Joshua N. Finger, and Scott A. Jelinsky
Biol Reprod, Mar 2007; 10.1095/biolreprod.106.059493

MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program: Dorothee Viemann, Katarzyna Barczyk, Thomas Vogl, Ute Fischer, Cord Sunderkötter, Klaus Schulze-Osthoff, and Johannes Roth
Blood, Mar 2007; 109: 2453 - 2460

The Contact Allergen Nickel Triggers a Unique Inflammatory and Proangiogenic Gene Expression Pattern via Activation of NF- B and Hypoxia-Inducible Factor-1alpha: Dorothee Viemann, Marc Schmidt, Klaus Tenbrock, Sybille Schmid, Verena Müller, Kerstin Klimmek, Stephan Ludwig, Johannes Roth, and Matthias Goebeler
J. Immunol., Mar 2007; 178: 3198 - 3207

A cassette system to study ES cell differentiation by inducible RNA interference: Daniel Wegmüller, Ines Raineri, Brigitte Gross, Edward J. Oakeley, and Christoph Moroni
Stem Cells, Jan 2007; 10.1634/stemcells.2006-010